Sensitivity is the percentage probability that a positive test will occur in a patient who is really experiencing rupture of membranes, or the proportion of actual positives which are correctly identified as such. In a multi-site hospital study involving 285 patients, ROM Plus resulted in an overall sensitivity of 99% (see IFU for details).

Specificity is the percentage probability that a negative test will occur in a patient who is not experiencing rupture of membranes, or the proportion of actual negatives which are correctly identified as such. Specificity also refers to the ability of the test to detect the correct result in the presence of interfering components that may be present in a sample matrix (i.e., blood, urine, semen, etc.). ROM Plus resulted in an overall specificity of 85%.