ROM Plus is a self-contained test kit that provides qualitative results for rupture of fetal membranes. The test does not require a speculum exam and is non-invasive, with only a simple vaginal swab sample required. Unlike other diagnostic products, ROM Plus’ cost effective cassette with built in test strip and timer delivers quick reliable results at point of care. Also, ROM Plus is the only test to use a combination of proteins, Placental Protein 12 (PP12, also known as IGFBP-1) and Alpha- Fetoprotein (AFP), specifically found in amniotic fluid. ROM Plus also uses both monoclonal and polyclonal antibodies on its test strip while other tests only use monoclonal antibodies.